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Measure Where Your

Accelerate cell culture optimization and simplify culture normalization by bringing measurement directly into your workflow with Rayo, the smallest compact microplate reader on the market.
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Built for the Way Modern Labs Work

Rayo is designed to operate directly inside modern laboratory workflows and allows your lab to:
Bullet Cerillo Eliminate workflow interruptions caused by plate transfers  
Bullet Cerillo Measure cultures directly within automated workflows  
Bullet Cerillo Capture higher-resolution growth data with frequent measurements  
Bullet Cerillo Accelerate experimental iteration during culture optimization  
Bullet Cerillo Normalize cultures quickly using rapid density measurements  

By integrating measurement within the experimental environment, your team can collect higher-quality growth data while maintaining stable experimental conditions.

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Eliminate Plate Transfers

When your lab is optimizing cell cultures, you repeatedly measure, analyze, and adjust experimental conditions. You may be evaluating how variables such as media composition, environmental conditions, cell density, or microbial strain performance influence culture growth and productivity.

Microplate readers allow your team to convert biological behavior into quantifiable datasets through optical density measurements across microplates. This enables you to monitor culture growth, generate growth curves, and compare culture performance across experimental conditions.


However, in many laboratories measurement systems are physically separated from the culture environment. This requires researchers to move plates between incubators, automation platforms, and centralized readers which introduces workflow interruptions and experimental variability that can slow optimization cycles.

Eliminate Plate Transfers

When your lab is optimizing cell cultures, you repeatedly measure, analyze, and adjust experimental conditions. You may be evaluating how variables such as media composition, environmental conditions, cell density, or microbial strain performance influence culture growth and productivity.

Microplate readers allow your team to convert biological behavior into quantifiable datasets through optical density measurements across microplates. This enables you to monitor culture growth, generate growth curves, and compare culture performance across experimental conditions.


However, in many laboratories measurement systems are physically separated from the culture environment. This requires researchers to move plates between incubators, automation platforms, and centralized readers which introduces workflow interruptions and experimental variability that can slow optimization cycles.

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Generate Reliable Growth Curves
Generate Reliable Growth Curves

By measuring optical density over time, your lab can analyze:

  • Growth rate differences between strains

  • Lag phase adaptation to media or environmental conditions

  • Culture yield and maximum density

  • Interaction dynamics in co-cultures

Growth curves typically include three phases:

Lag Phase - Cells adapt before active division begins

Exponential Phase - Cells divide rapidly and growth differences emerge

Stationary Phase - Growth slows as nutrients become limited

Frequent measurements allow your lab to generate higher-resolution growth curves and make more confident optimization decisions.

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The Optimization Cycle Driving Cell Culture Experiments
The Optimization Cycle Driving Cell Culture Experiments

Cell culture optimization follows an iterative experimental cycle.


Measure → Analyze → Optimize → Repeat


The faster your lab can measure culture performance, the faster you can refine experimental conditions and improve outcomes.

Rayo Brings Growth Measurement Closer to the Biology

 

Traditional microplate readers are large benchtop instruments typically located away from incubation environments or automation platforms. As a result, your team must manually transfer plates for measurement. These transfers disrupt experimental conditions and slow your workflow.


Rayo is designed to help your lab measure cultures closer to where the biology happens.


Its compact architecture allows the instrument to be placed:

  • on liquid-handling automation decks

  • inside anaerobic chambers

  • within controlled laboratory environments

This allows your team to measure cultures while maintaining environmental stability and reducing handling steps.

Solving the Challenges of Traditional Growth Measurement Workflows

Challenge: Plate Transfers Disrupt Experimental Conditions
Impact


In traditional workflows, plates must be removed from incubators or controlled environments and carried to a benchtop reader for measurement. These transfers can temporarily alter temperature, atmospheric conditions, or anaerobic stability, and potentially affects culture behavior.

 
Rayo Solution


Rayo’s compact architecture allows the instrument to be placed closer to the experimental environment, including inside anaerobic chambers or controlled laboratory spaces. This allows cultures to be measured while maintaining environmental stability.
Challenge: Centralized Instruments Interrupt Workflow Efficiency
Impact


Traditional microplate readers are often located away from incubators or automation platforms. Researchers must repeatedly pause experiments to move plates for measurement, adding manual steps and slowing overall experimental workflows.

 

 

Rayo Solution


Rayo can be placed directly on liquid-handling automation decks or within localized experimental setups. Measurement becomes part of the workflow rather than an interruption.
Challenge: Slower Optimization Cycles
Impact


Cell culture optimization requires repeated measurement, analysis, and adjustment. When measurements require manual transfers and workflow interruptions, each experimental cycle takes longer to complete.

 

 
 
Rayo Solution


By enabling measurement closer to where cultures grow, Rayo reduces workflow disruptions and supports faster experimental iteration.

 

Built for Modern Cell Culture Optimization

 

Modern cell culture optimization increasingly relies on automation, high-frequency measurements, and integrated laboratory systems.

With Rayo, your lab can:

Bullet Cerillo

Integrate measurement directly into experimental workflows

  
Bullet Cerillo

Generate higher-resolution growth datasets

  
Bullet Cerillo

Accelerate experimental iteration cycles

  
Bullet Cerillo

Improve reproducibility during culture optimization

  
With its compact, automation-ready design, Rayo enables researchers to integrate measurement directly into experimental workflows, supporting more efficient and reproducible culture optimization studies. Rayo helps your team measure cultures where your biology happens.

Traditional Readers

  • Centralized benchtop systems
  • Frequent manual transfers
  • Conditions change during transfer
  • Limited by handling
  • Lower temporal resolution
  • Difficult integration
  • Slower feedback cycles

Rayo

Built for the Modern lab
  • Integrated within workflows
  • Minimal plate movement
  • Measurements occur near cultures
  • Frequent measurements
  • Higher-resolution kinetic data
  • Designed for automation decks
  • Faster optimization cycles